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- Question
If a disease of the blood vessels caused the endothelial cells of the vessel to die, what effect would that have on the cellular activities associated with vasodilation?
Options- A. Nitric oxide would no longer be produced
- B. Smooth muscle cells could not be made to relax
- C. It would be more difficult to increase blood flow and reduce blood pressure
- D. All of the above
- Correct Answer
- All of the above
- 1. What is the name of the protein signaling molecule that alters glucose uptake, and where would its receptors be located?
Options- A. Insulin; many different cell types that use glucose for fuel
- B. Insulin; beta cells of the pancreas
- C. PDGF; the blood
- D. NGF; the nerves involved in simple reflexes Discuss
- 2. DiGeorge's syndrome is characterized by the lack of a thymus The mouse model closest to this human disease would be a
Options- A. knock-out mouse for RAG-1 and RAG-2
- B. knock-out mouse for a thymus
- C. nude mouse
- D. recombinant mouse for CD3 Discuss
- 3. Retinoblastoma is due to a mutation in a
Options- A. kinase
- B. tumor supressor
- C. cyclin
- D. viral gene Discuss
- 4. Infants are most susceptible to bacterial infection due to low circulating levels of IgG
Options- A. in utero (before birth)
- B. at 0-3 months of age
- C. at 3-12 months of age
- D. at 12-24 months of age Discuss
- 5. Chronic granulomatous disease results from a failure to perform oxidative burst. This deficiency would be most likely to interfere with
Options- A. CTL killing of viruses
- B. dendritic cell activation to become a mature APC
- C. infected cell processing of virus peptides
- D. macrophage intracellular killing of bacteria Discuss
- 6. Which of the following is true about a hydrophilic signaling molecule?
Options- A. Its receptor is located in the cytosol of the target cell
- B. It might trigger a signal cascade that causes some effect in a cell
- C. Since it can enter the cell, it directly affects some specific cell process
- D. It is a steroid Discuss
- 7. Why is it that inhaling nitric oxide reduces blood pressure only in the lung tissue and not elsewhere in the body*?
Options- A. Because other body tissues use a different signaling molecule
- B. Because nitric oxide cannot cross cell membranes and enter the blood
- C. Because nitric oxide breaks down quickly and thus cannot travel far
- D. None of the above Discuss
- 8. SH2 domains specifically bind to
Options- A. phosphorylated serine residues
- B. phosphorylated tyrosine residues
- C. GDP
- D. Ca2+ Discuss
- 9. Which of the following is a second messenger?
Options- A. lnositol 1,4,5-triphosphate
- B. Diacyl glycerol
- C. Phospholipase C
- D. Both (a) and (b) Discuss
- 10. The hormone or ligand can be considered as
Options- A. first messenger
- B. second messenger
- C. both (a) and (b)
- D. none of these Discuss
Cell Signalling and Transduction problems
Search Results
Correct Answer: Insulin; many different cell types that use glucose for fuel
Correct Answer: nude mouse
Correct Answer: tumor supressor
Correct Answer: at 3-12 months of age
Correct Answer: macrophage intracellular killing of bacteria
Correct Answer: It might trigger a signal cascade that causes some effect in a cell
Correct Answer: Because nitric oxide breaks down quickly and thus cannot travel far
Correct Answer: phosphorylated tyrosine residues
Correct Answer: Both (a) and (b)
Correct Answer: first messenger
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