Genetics terminology — What does the term ‘‘homologous chromosomes’’ mean in the context of a diploid organism?

Difficulty: Easy

Correct Answer: A pair of chromosomes of the same kind, one maternal and one paternal, carrying the same gene loci (homologs).

Explanation:


Introduction / Context:
Clear terminology is essential in genetics. ‘‘Homologous chromosomes’’ are central to understanding inheritance, meiosis, linkage, and mapping. This question distinguishes homologs from sister chromatids and clarifies ploidy implications.


Given Data / Assumptions:

  • Diploid cells contain pairs of homologous chromosomes.
  • Each homolog originates from a different parent.
  • Homologs carry the same gene loci in the same linear order, though alleles can differ.


Concept / Approach:
Sister chromatids are identical DNA copies generated during replication and joined at the centromere; homologous chromosomes are similar but not identical, representing maternal and paternal versions. Homology refers to shared loci, not necessarily identical sequence or alleles.


Step-by-Step Solution:

Rule out definitions that conflate homologs with sister chromatids.Reject options implying homologs must be haploid or are defined by size alone.Select the definition emphasizing same kind (same loci), one from each parent.


Verification / Alternative check:
Cytogenetics shows bivalents of homologs pairing in meiosis I, confirming the functional definition used in classical genetics.


Why Other Options Are Wrong:

  • a/b: Describe sister chromatids, not homologs.
  • c: Homologs exist as pairs in diploids, not necessarily haploid.
  • e: Size alone is insufficient; locus order matters.


Common Pitfalls:
Equating homology with 100% sequence identity; confusing meiosis I homolog separation with mitotic chromatid separation.


Final Answer:
A pair of chromosomes of the same kind, one maternal and one paternal, carrying the same gene loci (homologs).

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