Which of the following is not a prime number?

A prime number is a whole number greater than 1 whose only factors are 1 and itself.

Factors of 5 are 1, 5

Factors of 11 are 1, 11

Factors of 21 are 1, 3, 7, 21

Factors of 37 are 1, 37.

Hence, according to the definition of a prime number, 21 is not a prime number as it has more than two factors.