Name the journal that publish, the discovery of the first small-molecule inhibitors of the Streptococcus pyogenes Cas9 (SpCas9) protein by the team of researchers headed by Amit Choudhary.

Maitrayee Bose, Indian-origin cosmochemist along with Ziliang Jin, a postdoctoral scholar in Arizona State University's School of Earth and Space Exploration, have found water in asteroid Itokawa samples collected by the Japanese space probe Hayabusa. The research paper detailing the analysis of five of the particles from the asteroid samples was published in the journal Science Advances on 8th May 2019. Itokawa is a peanut-shaped S-type asteroid about 1,800 feet long and 700 to 1,000 feet wide. It circles the Sun every 18 months at an average distance of 1.3 times the Earth-Sun distance. The samples were collected from an area on Itokawa known as the Muses Sea, which is smooth and dusty.

UNICEF representative in India Yasmin Ali Haque lauded the contribution of Poshan Abhiyaan-a scheme by the central government in reduction of stunting, under-nutrition and anaemia in women and adolescents by providing monetary support via direct cash transfers. It was launched in 2017 by Prime Minister Narendra Modi in Jhunjhunu, Rajasthan.Quoting Haque, "Poshan Abhiyaan has got global recognition for its effort to eradicate malnutrition from India. Cash transfer is an additional support to the family income. The Poshan Abhiyaan is a massive step that realises the need for eradicating malnutrition".The latest UNICEF report states that one-third of the population suffers from at least one kind of malnutrition and the number would increase tohalf by 2025.According to the National Family Health Survey (NFHS)-4, 2015-16, one-fifth of the total population has a BMI less than 18.5, while one-fourth males and half of the total females are anaemic.According to the latest Global Nutrition Report, India accounts for one- third stunting of the global population. India topped the list with 46.6 million stunted children, followed by Nigeria (13.9 million) and Pakistan (10.7 million).

Gram Samridhi Yojana, a Rs 3,000 crore scheme funded by the World Bank and the Government of India, is being worked upon by the Ministry of Food Processing Industries in order to strengthen the unorganised food processing sector concentrated in rural areas. World Bank will be giving Rs 1,500 crore and Rs 1,000 crore will be borne by the Centre while state governments will put in Rs 500 crore. The scheme will be run in Uttar Pradesh, Andhra Pradesh, Maharashtra and Punjab for a five-year period in the initial phase and thereafter in other states of the country. NITI Aayog has given its approval to the scheme and now the proposal is pending with the Expenditure Finance Committee for clearance.

The Government of Nepal has launched an ambitious 45-day 'Everest Cleaning Campaign' to bring back tonnes of trash from Mt. Everest from 14th April 2019. The campaign is led by Solukhumbu district's Khumbu Pasanglhamu Rural Municipality and aims to collect nearly 10,000 kgs of garbage from Mt. Everest. Every year, hundreds of climbers, Sherpas and high altitude porters make their way to Everest, leaving behind tonnes of both biodegradable and non-biodegradable waste - including empty oxygen canisters, kitchen waste, beer bottles and faecal matter - on the highest peak, which has lately acquired notoriety as the "world's highest garbage dump". The collected waste will then be showcased in Namche town, before being ferried down to Kathmandu, where it will once again be showcased on World Environment Day (WED-2019) on June 5. After that, it will finally be sent out for recycling.

The Union Cabinet approved the listing of 7 Central Public Sector Enterprises (CPSEs) on the stock exchanges via Initial Public Offering (IPO) or Follow-on Public Offer (FPO). The companies that will go for IPOs include Telecommunication Consultants (India) Ltd., RailTel Corporation India Ltd., National Seed Corporation India Ltd., Tehri Hydro Development Corporation Limited, Water & Power Consultancy Services (India) Limited and FCI Aravali Gypsum and Minerals (India) Limited. Kudremukh Iron Ore Company Limited will go for an FPO.

According to a new collaborative study by the Queen's University Belfast and Aberystwyth University in the UK, the sun's magnetic field is ten times stronger than previously thought. Using the Swedish one-metre Solar Telescope at Roque de los Muchachos Observatory, in the Canary Islands, David Kuridze studied a particularly strong solar flare which erupted near the surface of the Sun on September 10, 2017. A combination of favourable conditions and an element of luck enabled the team to determine the strength of the flare's magnetic field with unprecedented accuracy. The researchers believe the findings have the potential to change our understanding of the processes that happen in the Sun's immediate atmosphere. The study found that the sun's corona extends millions of kilometres above the surface, measuring 1,400,000 kilometres across -- 109 times larger than Earth and 150,000,000 km from Earth. Solar flares appear as bright flashes and occur when magnetic energy that has built up in the solar atmosphere is suddenly released.

Chang'e-4 lunar probe, a Chinese space probe, touched down on the far side of the moon. The probe, which has a lander and a rover, that was launched in December made the soft landing and transmitted the first-ever close-range image of the far side of the moon. It touched down at a targeted area near the moon's south pole in the Von Karman Crater. The purpose of the Chang'e-4 includes astronomical observation, surveying the moon's terrain, landform, and mineral makeup, and measuring the neutron radiation and neutral atoms to study the environment of its far side. The moon is tidally locked to Earth, rotating at the same rate as it orbits our planet, so most of the far side or dark side is never visible to us. Previous spacecraft have seen the far side, but none has landed on it. China's space agency hailed the event as a historic first and a major achievement for the country's space programme.

Light Combat Aircraft (LCA) Tejas progressed towards manufacture in an enhanced, battle standard format on December 31. The LCA is being designed and developed by the Aeronautical Development Agency (ADA) in Bengaluru. A new limited clearance from military airworthiness certifier CEMILAC for the Indian fighter green-lights its production in a superior lethal version. HAL aims to get the first aircraft out in late 2019. The Indian Air Force (IAF) has asked Hindustan Aeronautics Limited (HAL) to make 40 LCA aircraft. Of this, 20 will be in the advanced Final Operational Clearance (FOC) format. Another 20 are in the earlier Initial Operational Clearance (IOC) version. The IAF has modified and upgraded its trainer requirement in its old package order of 40 LCA aircraft.

Karnataka defeated Maharashtra to win their maiden Syed Mushtaq Ali Trophy at the Holkar Cricket Stadium in Indore. With the win, Karnataka set a record of most number of wins in a row by an Indian domestic team as they won 14 T20 matches to lift the coveted T20 trophy.

The 16th meeting of the Canada-India Joint Working Group on Counter-Terrorism and its Expert Sub-group was held in Ottawa to provide detailed briefings on their respective nation's counter-terrorism priorities, strategies, and legislative frameworks. The meeting has reviewed the threats posed by terrorist groups worldwide and in their respective countries and regions.