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- Question
A selective IgA deficiency would be expected to result in problems with
Options- A. bacterial infections
- B. infections following dental work due to bacteria entering the bloodstream
- C. mucosal pathogens
- D. pathogens which can survive inside macrophages
- Correct Answer
- mucosal pathogens
- 1. To treat HIV infections using drugs, the major problem is that
Options- A. the drugs that are good inhibitors cannot by synthesized
- B. the drugs interfere with normal digestion
- C. the virus particles with altered (mutant) proteases arise
- D. the drugs are rapidly degraded Discuss
- 2. An example of an immunodeficiency disorder is
Options- A. thyroiditis
- B. rheumatic fever
- C. systemic lupus erythematosus
- D. AIDS Discuss
- 3. The chemical, typically released by the body in an allergic response is
Options- A. histamine
- B. allergens
- C. antihistamines
- D. perforins Discuss
- 4. The primary reason for AIDS, a deadly disease is that it
Options- A. is caused by a virus
- B. is caused by a bacterium
- C. destroys key components of the body's internal defense system
- D. causes a breakdown of the body's inflammatory response Discuss
- 5. A monoclonal antibody (mAb) specific for the 2,4-dinitrophenyl (DNP) hapten might also bind
Options- A. Leu or Ileu
- B. His or Pro
- C. Tyr or Phe
- D. Ser or Thr Discuss
- 6. Bone marrow given to an infant with SCID must
Options- A. be irradiated to eliminate GVHD
- B. contain mature T cells that can begin making immune responses immediately
- C. come from a donor that shares some MHC alleles with the recipient
- D. come from one of the child's parents Discuss
- 7. Combined cellular and humoral immune deficiencies result from lack of all of the following except
Options- A. a thymus
- B. class II MHC
- C. HIV infection of CD4+ T cells
- D. transporter of antigen peptides (TAP) Discuss
- 8. Which of the Rous sarcoma virus has a homologous cellular protein?
Options- A. c-src
- B. v-src
- C. v-ha-src
- D. v-ha-ras Discuss
- 9. Difficulties with somatic gene therapy arise from all of the following except
Options- A. GVHD caused by mature T cells in the transplanted cells
- B. inserting a gene so that it will function properly
- C. limited life span of more mature hematopoietic cells
- D. transducing genetic material into stem cells Discuss
- 10. X-linked hyper IgM syndrome, resulting in high levels of serum IgM and low levels of serum IgG, is caused by a defect in CD40L expression. The specific immune event that would be prevented by a defective CD40L would be
Options- A. activation of B cells by T-independent antigens
- B. failure of B cells to provide co-stimulation for Th2 activation
- C. failure of Th2 cells to provide co-stimulation for B cell isotype switching
- D. failure of Th2 cells to provide co-stimulation for B cell proliferation Discuss
Disease Associated with Immune System problems
Search Results
Correct Answer: the virus particles with altered (mutant) proteases arise
Correct Answer: AIDS
Correct Answer: histamine
Correct Answer: destroys key components of the body's internal defense system
Correct Answer: Tyr or Phe
Correct Answer: come from a donor that shares some MHC alleles with the recipient
Correct Answer: transporter of antigen peptides (TAP)
Correct Answer: c-src
Correct Answer: GVHD caused by mature T cells in the transplanted cells
Correct Answer: failure of Th2 cells to provide co-stimulation for B cell isotype switching
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