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Home Biochemistry Antigen Comments

  • Question
  • Very low doses of antigen may induce


  • Options
  • A. hypersensitivity
  • B. immunological ignorance
  • C. low zone tolerance
  • D. low zone immunity

  • Correct Answer
  • low zone tolerance 


  • Antigen problems


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    • 1. Which of the following is incorrect with regard to antigen epitopes?

    • Options
    • A. An epitope may be shared by two different antigens
    • B. A protein molecule usually contains multiple epitopes
    • C. B cells bind only processed antigen epitopes
    • D. Epitopes may be linear or assembled
    • Discuss
    • 2. Which of the following (s) is/are serine proteases?

    • Options
    • A. Chymotrypsin
    • B. Trypsin
    • C. Elastase
    • D. all of these
    • Discuss
    • 3. The cleavage specificity of trypsin and chymotrypsin depend in part on the

    • Options
    • A. proximity of Ser 195 to the active site or specificity pocket
    • B. size, shape, and charge of the active site or specificity pocket
    • C. presence of a low-barrier hydrogen bond in the active site or specificity pocket
    • D. absence of water in the active site
    • Discuss
    • 4. The E.coli pyruvic acid dehydrogenase complex is reported to

    • Options
    • A. decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2
    • B. Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2
    • C. retard the reduction of pyruvic acid to acetyl Co A and CO2
    • D. Catalyze the reduction of pyruvic acid to acetyl Co A and CO2
    • Discuss
    • 5. The role of Asp 102 and His 57 during trypsin catalysis is to

    • Options
    • A. neutralize the charge on the other's side chain
    • B. keep the specificity pocket open
    • C. function as a proton shuttle
    • D. clamp the substrate into the active site
    • Discuss
    • 6. CD antigens

    • Options
    • A. allow leukocytes to recognize antigen
    • B. are each expressed on only one cell type
    • C. are expressed on immune cells to mark them for separation
    • D. function as receptors for cytokine and CAMs
    • Discuss
    • 7. A molecule that can be covalently linked to a non-immunogenic antigen to make it an immunogen is called a (n)

    • Options
    • A. adjuvant
    • B. carrier
    • C. hapten
    • D. mitogen
    • Discuss
    • 8. The ability of an antigen to induce an immune response does not depend on the antigen's

    • Options
    • A. ability to enter the thyroid
    • B. degree of aggregation
    • C. dose
    • D. size
    • Discuss
    • 9. During the lag period between antigen contact and detection of adaptive immunity,

    • Options
    • A. antigen is hidden from the immune system in macrophages
    • B. innate immune effectors are eliminating antigen
    • C. innate immunity blocks the activation of adaptive immune effector cells
    • D. new B and T cells with the appropriate antigen specificity must be produced in the bone marrow
    • Discuss
    • 10. For specific antigen recognition by T cells,

    • Options
    • A. antigen is bound by a T cell membrane antibody
    • B. denaturation of antigen does not reduce epitope recognition
    • C. MHC molecules are not required
    • D. antigen exposure during T cell maturation is required
    • Discuss


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