A callous person is insensitive or emotionally hardened.
Hence, Callous is the opposite of Sympathetic, kind hearted, sensitive, nice,...
Commissioned means Authority granted for a particular action or function.
Here, in the given options Dismiss is the only word which is opposite in meaning to commissioned.
Hence, Antonym of Commissioned is Dismiss.
Given word is O B S E R V A N T. After making the change as given in the question, we get the following arrangement:
T N A V R E S B O.
A N N I H I L A T I O N => N I A N L A H I O N T I
After changes, A is 6th from left.
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